MultiplexDX

COMPANY OVERVIEW

The company has representation in both  U.S. and European markets. The U.S. site is located in close proximity to the National Institutes of Health as well as the Food and Drug Administration. The collaborators of MultiplexDX are from the world’s most prestigious scientific organizations including the National Cancer Institute, Rockefeller University, Albert Einstein University, Vanderbilt University, Cornell University, Queens University (Canada), Hebrew University of Jerusalem (Israel), and the Max Delbrück Center for Molecular Medicine (Germany).

The mission of MultiplexDX is to eliminate cancer misdiagnosis by creating reliable, 100% accurate, quantitative and affordable diagnostic tests. MDX’s IP-based solutions combine visualization and sequencing technologies to quantify 7 or more cancer markers to give each diagnosis a specific “barcode,” which will indicate not only the cancer type but also the duration of personalized treatment for that cancer. As our name suggests, we also use multiplexing; cross-testing and verifying the same result from at least two independent sources. By embedding numbers into pictures and vice-versa, our diagnostics shed light on the patient’s set of cancer markers and profile, enabling oncologists to make evidence-based decisions and prescribe treatment quickly, directly and more accurately.

Based on its proprietary innovative technologies, MultiplexDX offers the following portfolio of product lines and services: COVID-19 diagnostics; Custom Oligonucleotides; RNA Sequencing; RNA FISH; Bioinformatics; Personalized Diagnostics.

MultiplexDX products and services offer a variety of cost-effective, innovative and high quality solutions: the most precise sequencing analysis, the simplest and gel-free sequencing protocol, the simplest FISH protocol, the most stable and specific FISH probes, the most precise cancer profiling, the most accurate biomarker quantification. Among the company’s most ambitious plans is the development of hi-definition 3D digital pathology services using a variety of proprietary MultiplexDX technologies.

INNOVATIONS

As every cancer is unique, every patient deserves a personalized diagnosis that leads to tailored, effective, and life-saving treatment. MultiplexDX is launching its next generation of revolutionary diagnostic tests, which can precisely identify and quantify cancer markers. Combining multiplex quantitative RNA fluorescence in situ hybridization (RNA FISH) and RNA sequencing (RNAseq) technologies, MultiplexDX’s biotechnical innovation unifies biomarker quantification, histology, and visualization with single-cell resolution. The unmatched complexity and accuracy of our tests (simultaneous visualization and quantification of seven or more cancer markers) will surpass the limitations of today’s diagnostic tools, and give each diagnosis a specific “barcode” for its cancer type.

MultiplexDX’s products and services will reach beyond the limits of existing visualization methods (e.g. immunohistochemistry (IHC)) and RNA based tests (e.g. RNAseq, qPCR). Conventional visualization assays lack precise quantitative data, while quantitative RNA-based molecular diagnostics miss crucial tissue morphology and localization data. Thus, MultiplexDX’s innovative cancer diagnosing technology will combine the best of these two methods, bringing together localization on a cellular level and quantitative biomarker signal.

TEAM

Pavol Cekan, PhD

Pavol Cekan, PhD

Founder/CEO

Pavol is an innovative leader with over 15 years of experience at the top research and government institutions. He received his doctorate in chemistry from the University of Iceland in 2009. As a Postdoctoral Associate at Rockefeller University, Pavol developed methodology for the retention of nucleic acids in tissue sections during RNA in situ hybridization and preparation/validation of specific oligonucleotide probes and fluorescent signal amplification processes.

Before founding MultiplexDX, he was working at a premier cancer research organization - National Cancer Institute (NCI) for 4 years. Pavol is a PhD trained Nucleic Acid Chemist/Biochemist focusing on modified oligonucleotide synthesis and spectroscopic analysis of nucleic acid structure/function.

Pavol has 35+ scientific publications, is the inventor of 3 granted patents, and is a member of the Science Advisory Board of the Slovakian Ministry of Health. Pavol is a member of an exclusive network of CEOs called Mindshare and won several prestigious awards highlighting his business and scientific achievements.

Pavol Cekan, PhD

Founder/CEO

Pavol Cekan, PhD
Peter Kilián, PhD

Peter Kilián, PhD

COO

For 7 years, Peter worked as a Biotechnology consultant at Neulogy, a market leader in providing complex consulting and incubation services to research institutes and entrepreneurs in all parts of Slovakia. Peter was also a Managing Director at BioScience Slovakia, a biotechnology company focused on development of innovative diagnostics and treatment tools in the area of cancer and virology.

Peter is experienced in technology transfer, conception and implementation of projects funded by EU structural funds, topics he addressed while working as Managing Director at BioScience Slovakia. He is an EPO certified trainer in the field of intellectual property. Peter studied Biomedical physics at Comenius University in Bratislava and since 2005 holds a PhD in Physiology and Biophysics from Université de Sherbrooke in Canada.

Peter Kilián, PhD

COO

Peter Kilián, PhD
Petra Lipnicka

Petra Lipnicka

Chief Strategy Officer

Petra received her Master of Science degree (Ecology and Environmental Sciences) from Technical University of Zvolen in 1999. She has over 15 years of executive and management experience in European projects aimed at enhancing the R&D infrastructure in Slovakia and other R&D projects.

She specializes in management of R&D, technology commercialization, tech transfer, start-ups, fundraising and science communication. She is also the architect of a national science festival with ca. 180K visitors in a single day. Petra is a former Chairwoman and CEO of Neulogy, innovation boutique consultancy (now part of Civitta Group). For many years, Petra managed and executed Neulogy‘s mission to help start-ups, companies, academic institutions and research centers to conduct world class R&D projects as well as having access to financing from both public and private sources, including seed and venture capital. She is a Chairwoman of the Board at the Slovak Organization for Research and Development Activities, an NGO supporting the research ecosystem in Slovakia.

Petra Lipnicka

Chief Strategy Officer

Petra Lipnicka
Evan Paul, PhD

Evan Paul, PhD

Chief Scientific Officer

Evan is a dynamic biomedical scientist with over 15 years of experience conducting research in molecular biology and analytical chemistry, with an emphasis on discovering novel biomarkers and therapeutic targets.

He received a dual PhD in Integrative Physiology and Neuroscience from the University of Colorado Boulder, USA, where he directed an analytical chemistry core unit to detect small molecule neurotransmitters in the brain. He also received a minor degree in Business Administration. He continued his research as a postdoc in Alon Chen’s prestigious laboratory jointly sponsored by the Max Planck Institute of Psychiatry in Munich, Germany and the Weizmann Institute of Science in Rehovot, Israel. There he developed protocols using next generation sequencing and in situ hybridization to quantify and visualize, respectively, microRNAs in order to identify novel biomarkers for psychiatric disorders.

He has published 25+ scientific papers and book chapters in prestigious journals like Nature Neuroscience and Neuron, with the latter resulting in a patent for a novel microRNA biomarker for depression that was licensed to miCure therapeutics Ltd.

Evan Paul, PhD

Chief Scientific Officer

Evan Paul, PhD
Peter Kocúr

Peter Kocúr

Strategic Business Advisor

Peter is a senior finance executive, and board member with strong commercial acumen and tangible accomplishments across diverse pharmaceutical markets both in Europe and Asia.

During his 18 years tenure with Novartis, one of the global pharmaceutical leaders, he spearheaded worldwide finance operations of a multi-billion enterprise, led publicly listed entities as well as commercial operations in the most complex markets.

Heading Business Development and Licensing operations, he has been consistently recognized for designing and executing innovative external collaborations and transformative deals. Before Novartis, he spent several years in various advisory and consultancy roles with blue-chip companies in Europe.

Peter Kocúr

Strategic Business Advisor

Peter Kocúr

FOUNDERS

Pavol Cekan, PhD

Pavol Cekan, PhD

Founder/CEO

Pavol is an innovative leader with over 15 years of experience at the top research and government institutions. He received his doctorate in chemistry from the University of Iceland in 2009. As a Postdoctoral Associate at Rockefeller University, Pavol developed methodology for the retention of nucleic acids in tissue sections during RNA in situ hybridization and preparation/validation of specific oligonucleotide probes and fluorescent signal amplification processes.

Before founding MultiplexDX, he was working at a premier cancer research organization - National Cancer Institute (NCI) for 4 years. Pavol is a PhD trained Nucleic Acid Chemist/Biochemist focusing on modified oligonucleotide synthesis and spectroscopic analysis of nucleic acid structure/function.

Pavol has 35+ scientific publications, is the inventor of 3 granted patents, and is a member of the Science Advisory Board of the Slovakian Ministry of Health. Pavol is a member of an exclusive network of CEOs called Mindshare and won several prestigious awards highlighting his business and scientific achievements.

Pavol Cekan, PhD

Founder/CEO

Pavol Cekan, PhD
Vladimir Wolf, PhD, MBA

Vladimir Wolf, PhD, MBA

Co-founder

Vladimir has been working over 10 years in the biotechnology industry, in positions ranging from scientist to Director of Business Development. He received his PhD in molecular biology from the University of Bern. For 6 years, Vladimir was a Visiting scientist at the National Cancer Institute, USA.

In 2004, he joined Trophogen as a Senior Scientist for the first time and then returned to the company in 2011 after a three year break. During his time at Trophogen, he advanced from scientist to Director of Business Development and, as such, played a pivotal role in securing licensing deals with Zoetis, the world’s largest animal health company. Before joining Trophogen for the second time, Vladimir worked as a Manufacturing scientist at the diagnostics company QIAGEN. He designed and implemented new manufacturing processes in compliance with CGMP regulations. He was also sponsored by QIAGEN to receive his MBA in Business Integration from the University of Wurzburg.

Vladimir has 20+ scientific publications.

Vladimir Wolf, PhD, MBA

Co-founder

Vladimir Wolf, PhD, MBA

CLIENTS

OUR ACHIEVEMENTS